In terms of Destro, it's hard to get past the cartoon and even the CGI movies. Personally, I see his voice like Avery Brooks. That'd be Benjamin Sisko of Deep Space 9 (Or "A Man Called Hawk").

In terms of Cobra Commander, I feel that the guy went thru a lot of changes throughout the cartoon. From fairly competent duder who wanted to take over the world to a lackey and buffoon to a snake, then a half human. His voice changed over time to. I'm not the biggest fan of the cartoon anymore, but his voice has stuck with me. The personality on the other hand... He is NOT anything like the cartoon in my Joeverse.

For #2, there have been a lot of characters that I can't seem to integrate into my Joeverse. With the exception of Falcon, my Joeverse is based on nu skulpts so if someone like Ice Cream Soldier wasn't remade, then he's not part of verse. Someone like Quick Kick and Doc are dead (as per the comic). But when Hasbro brought in someone like Sgt Hacker, I had no real place for him. I didn't care for the figure, y'know? Red Spot and Widescope have a hard time in verse. Course, I just gave Red Spot away. But Widescope? You'd think there'd be a spot in my verse for a SWAT/Security type of guy, but the reality is, there isn't. I can't use him on normal military missions due to his paint scheme. Someone like Footloose and Crosshair are far more versatile. And versatility is what I need in my 'verse.